Compounded semaglutide
NewSelf vs RxPepsDirect
Quick answer
RxPepsDirect costs $80 a real month and NewSelf costs $170 — a difference of $90 a month, or $1,078 a year. Both figures are computed from what each seller actually charges and how often, not from the price on its landing page.
Checked in . Both sellers are re-checked on the same schedule; a price either side changes after that date will not be reflected here until the next check.
NewSelf or RxPepsDirect?
RxPepsDirect is the cheaper way to start, at $80 a month against $170 for NewSelf, but the order flips at the top dose: there NewSelf costs $170 and RxPepsDirect $350. RxPepsDirect's figure includes a monthly fee of $55 that NewSelf does not charge. Only NewSelf reaches Alabama, Arkansas, California, Georgia and 19 more states, while only RxPepsDirect reaches District of Columbia and Louisiana, going by where each says it ships. NewSelf received an FDA warning letter in February 2026; RxPepsDirect has none on record.
What each one bills
| NewSelf | RxPepsDirect | |
|---|---|---|
| True monthly cost | $170 | $80 |
| Advertised as | $100 | $64 |
| Charged | every calendar month | every 30 days |
| Each charge | $170 | $25 |
| Price basis | the same at every dose | a starting-dose price that climbs |
| Mandatory recurring fee | none found | $55 a month |
| States it names | 49 states | 28 states |
| FDA warning letter | yes | none on record |
Where they actually differ
- They bill on different clocks. NewSelf charges every calendar month and RxPepsDirect charges every 30 days. That alone changes what a “month” costs, which is the whole reason this index recomputes every price.
- One price holds and the other climbs. NewSelf’s price is the same at every dose; RxPepsDirect’s is a starting-dose price that climbs. See what titration does to an advertised figure.
- Only one carries a mandatory recurring fee. RxPepsDirect: $55 a month. 360 of 382 sellers charge nothing like it.
- What they advertise is not what they bill. NewSelf advertises $100 and bills $170; RxPepsDirect advertises $64 and bills $80.
How we know
Both figures were read on the seller’s own site and recomputed over a 30.4375-day calendar month from the charge and the billing period it covers. Neither is a seller’s own “/mo”. The full working for each — the charge, the period, the arithmetic and the date it was read — is on its own page: NewSelf and RxPepsDirect. The method is set out in how we verify.
To compare any two sellers in the index rather than these two, use the comparison tool.