Compounded semaglutide

Is compounded semaglutide still cheaper than Wegovy?

For most of the market, yes — and by less than the headline suggests, because the brand’s advertised price is not its ongoing one. At the expensive end of the compounded market the comparison has already inverted.

Quick answer

Wegovy’s ongoing injection price is equivalent to $379.38 a calendar month once an introductory offer ends. Of the 379 compounded sellers with a price on this index, 374 come in under that and 5 do not. The median is $199.

Wegovy injection 0.25–2.4 mg: $349 per 28-day fill after any introductory offer. The comparison excludes oral Wegovy and HD 7.2 mg, which costs $399 per fill. Eligibility and other terms apply. All comparison amounts use 30.4375 days: each 28-day brand fill × 30.4375 ÷ 28. These are cost equivalents, not checkout charges. Manufacturer terms (checked October 2026).

What the approved product actually costs now1

The modeled injection strengths, 0.25, 0.5, 1, 1.7 and 2.4 mg, share an ongoing $349 charge for four weekly pens. That is $379.38 per calendar month. HD 7.2 mg costs $399 per fill and oral Wegovy has separate pricing; neither is included here.

The $199 is an introductory rate1

eligible new patients pay $199 per 28-day fill for their first two fills at 0.25 or 0.5 mg through December 31, 2026, then $349 per 28-day fill; eligibility and other terms apply. Our ongoing comparison excludes this temporary offer.

How that compares with the compounded market2

Against $379.38, the cheapest seller on this index is $53.81 and the median is $199. The saving at the median is real — roughly $180.38 a month — and it is a long way from the order-of-magnitude difference the compounded market was built on.

What the compounded market charges, per month

0244872sellers$50 to $75 a month — 1 seller$75 to $100 a month — 18 sellers$100 to $125 a month — 17 sellers$125 to $150 a month — 43 sellers$150 to $175 a month — 46 sellers$175 to $200 a month — 95 sellers$200 to $225 a month — 32 sellers$225 to $250 a month — 38 sellers$250 to $275 a month — 28 sellers$275 to $300 a month — 35 sellers$300 to $325 a month — 6 sellers$325 to $350 a month — 11 sellers$350 to $375 a month — 3 sellers$375 to $400 a month — 4 sellers$425 to $450 a month — 1 seller$525 to $550 a month — 1 sellermedian $199.00Wegovy, direct$379$0$100$200$300$400$500true cost per calendar month
379 sellers publish enough to compute a real month. Half of them sit between $162 and $249. 5 charge more than Wegovy does direct.

One row per seller. All comparison amounts use 30.4375 days: each 28-day brand fill × 30.4375 ÷ 28. These are cost equivalents, not checkout charges. Brand: $349 per 28-day fill = $379.38 per calendar month, injection 0.25–2.4 mg only; introductory offer excluded.

True monthly cost by $25 price band, 379 sellers. Median $199.00. Wegovy direct: $379.38 at modeled injection doses.
Price bandSellersWhich sellers
$50 to $751Fidelity Medical Clinic
$75 to $10018Collective, NextMeds, Lean Meds, RxPepsDirect, BiltRx, Embody, Potere Health MD, Mondae, altRX, Science & Co, CoreAge Rx, Eden, Liv Body, Teleios Health, Trinity Meds, Lttl, Queen RX, Factor Health MD
$100 to $12517Stealth Health, 10Rx, Aspire Health, RxPros, Mint Med, HealthHub, Valhalla Vitality, SnagRx, Pepti, OurView Health, Blis MD, Lumen Meds, Trava Health, Kongo, PreventiveMD, VevaRX, Ascend Medical
$125 to $15043Healthicare, Bliv, Zeuss, Strut Health, Alternate Health Club, Brightmeds, BioGlow Health, Liberty, Bayan Health, EverSlim, Live Vital, NuuVim, Somi Health, NexLife, Cielo, MyFastRx, Rewinding RX, Elevate Health, TrueMe, Rylo Health, Tablet Health, Somira Health, WellMedr, Mochi Health, Lavender Sky Health, 50 Stars Health, Yucca Health, Fridays, OrderlyMeds, Novi, Ivologist, VitaFusions IV, Sunlight, Ondra Health, MedLeanRx, Luma Meds, NuBloom, Nirwana Health, Auren Rx, Idgie Health, CeliaRx, LevelUp Rx, Precision Telemed
$150 to $17546TRYM Health, Trellis Vitality, Metaboost Rx, VitaStir, MaxLife, Bodi Envi, Woodwork, Brello Health, HelloWellness, Coby Health, bmiMD, Trillium Meds, Wholesome Clinic, Citizen Meds, Harbor, Center for Medical Weight Loss (CMWL), Rehydra+ Wellness, SexyMD, FormBlends, HealthRX, LifespanningRx, Invyncible, TeleZen MD, Livea, Reset Solutions, GobyMeds, Alloy, Actin, Open Water Rx, Ark Health, EOS Health, PepHaūs, Whoosh Wellness, Coivas, Jyra Health, Luci, CLYR Health, NewSelf, Effecty, YourHealthRx, SynergenX Health, Velvet Rx, Gimme Care, Blue Sky MD, WeightlessRx, Primary Clinic (Direct GLP)
$175 to $20095Cora Health, Trimi Health, LovelyMeds, Nova MD, Try Ageless, Heros Health, Ozari Health, FitFlow, Genesis Health, Voxy, Rx.com, Ivy Rx, FORM, GOAL.MD, Noom, TrimRx, NativeMed, DudeMeds, Good Girl Rx, YourEra, Vytora Health, DreamHug Medical, Green Cap Health, Nucore Health, Blue Haven RX, Zera Health, AZ Health, Fitness RX, DoctorAdam, Edessa, Big Easy Weight Loss, Carocare Wellness, Midi Health, Joi + Blokes, NP2GO, T2D.com, Näky, Fresh Day Meds, Dollar Dad Club, LumiMeds, Maves, PlexusDx, Revel RX, Obu Health, Candor Rx, WePeptideRx, Bionomy Health, Nex Gen Health Rx, Amble, Polly, OnlyRx, LIV by WellNow, Regenics, Belle Health, Boston Medical Group, Good Life Meds, Shed, TOM Weight Loss, Care Bare Rx, Get Thin MD, Concierge MD LA, NiceRx, RxION Health, Corsica Health, Heva Health, Loop Health, Spry, PauseRX, Neo Soma Healthcare, Ascend Vitality, VigorMeds, MANÜ Telehealth, Fifty 410, Transparent Meds, Medsol RX, RxSaludable, Jently, HumeCare+, BloomWell Rx, ElixaMD, Kina, Measured, Next Vial, TelePeptide, California Trim Clinic, Tuyo Health, Medro, Youth & Soul, EdgeRx, RENN Health, Oria Meds, Andrew Meds, Renlo Health, Arc-1, Recovery Delivered
$200 to $22532Optimized Health, Harmony Wellness Clinic, Glam Health, Kin Meds, Fierce Health, Wellspring Longevity Clinic, Longevixx, Superior Remedies, Lyfe Rx, ShapeIn Rx, KERNX Health, Always Wellness and Recovery, Rixa Health, NuviaRx, The Calibrate Clinic, AquaVita NextGen, Refills, Joey Med, Harper Meds, REMEVi, LeanDose, Nolu, Pallas Health, CoraDoc, Raeliva, Fitish, ARSYNL Rx, Avono Health, Semaglutide Online, Bon Health, AbundRX, DrBrainRx
$225 to $25038Tonik Wellness, boostAGErx, Luvo Health, AVARA Rx, CaliberRx, Shapely, Vita Bella, SurpassMD, MadeMed, Vaylen, Invigor Medical, FMmeds, Dr. Gillis' Wellness Center, Lumora, Levers Health, InstaRX, Goldspan Health, Peak Wellness, SkinnyRx, TMates, Synergy Rx, ReadyRx, Gala, Elara Health and Wellness, Elara MD, Mevo Health, Remi Meds, He & She MD, Cabana, Zappy Health, RxSpan MD, NuDay Rx, Telos Rx, LevelsRx, AlyveRx, AHBARx, JustAnswer Weight Loss, Maximus
$250 to $27528Oak, Breeze Meds, Believe Health, Eviora MD, New Wave Health, RX Bella, Superpower, MyDrHank, The Edit, HeliMeds, DadVantage Men's Health, ElitePhysiqMD, RNK Health, Wellorithm, Dr. Arevitalize, ElleS, Go Vida Plena, Bloom MD, Enhance MD, Tyde Wellness, Aquivia Health, Signos, Options Medical Weight Loss, UR Meds, Fitstry, Prime Doctor RX, Immortals, Ivim Health
$275 to $30035Premium Health, HealthOn, Bodybuilding Health+, VirtualCare2Go, June Health, Tryozi, PeterMD, PrescribedRX, LaSara Medical Group, Care Clinics, Elevated Health, Iron Med RX, Henry Meds, Direct Meds, Roen Rx, Freya Meds, FitRx, AM Rx, Eloria, Better U Care, Independent Wellness, Willow, MyStart Health, MD Total Wellness, Curex, MediRX, Rivo Health, TeleCareSpot, RestorLife Med, Society of You, Apex MD, Intimate Rose, tru Weight Loss, Aspen, MEDGm
$300 to $3256MDExam, Clinic Secret, BetterMe Rx, Nu Image Medical, Found, Vyora Wellness
$325 to $35011EllieMD, MEDVi, Remedy Meds, Fella Health, Sprout Health, Claya, Lean Rx, Prime Health, Omzo, iThriveMD, Lemonaid Health
$350 to $3753Vital Edge, The Aesthetic Concierge, Revive Meds
$375 to $4004Zealthy, WeightCare, Gaya Wellness, Rivas Medical Weight Loss
$425 to $4501Injectco
$525 to $5501ReflexMD

The distribution matters more than the median. This is not a market with one price; it is a market with a wide spread, and which side of the brand you land on depends entirely on which seller you pick.

Where the comparison inverts2

5 of 379 sellers on this index charge more per calendar month than the approved product does. For those, the compounded vial is not a cheaper alternative to Wegovy — it is a more expensive one, without the label.

Advertised against what it actually costs

  • Advertised as
  • Actually costs
  • the gap
ReflexMD$297 → $540+$243.27ReflexMD: advertised $297.00, actually $540.27Zealthy$151 → $379+$228.00Zealthy: advertised $151.00, actually $379.00Nu Image Medical$99 → $310+$211.16Nu Image Medical: advertised $99.00, actually $310.16BetterMe Rx$99 → $303+$204.29BetterMe Rx: advertised $99.00, actually $303.29AM Rx$106 → $297+$191.00AM Rx: advertised $106.00, actually $297.00Fella Health$149 → $325+$176.03Fella Health: advertised $149.00, actually $325.03Sprout Health$149 → $325+$176.03Sprout Health: advertised $149.00, actually $325.03Revive Meds$199 → $369+$170.00Revive Meds: advertised $199.00, actually $369.00$0$200$400$600cost per calendar month
231 sellers put a monthly price on their own page that their own billing does not produce. ReflexMD advertises $297.00 a month and bills $540.27 — $243.27 more every month, or $2,919.24 over a year. Across all 231, the understatement comes to $19,197.36 a year. Every gap runs the same way: the advertised figure is always the smaller one. The chart shows the 8 largest; the rest are in the index.

Advertised is the seller's own per-month figure. True is that same charge divided by the days it covers, times 30.4375 — the average calendar month. A seller appears only where the two differ by more than 1%.

Advertised monthly price against true monthly cost. The 8 largest gaps of 231 sellers where the two differ.
SellerAdvertisedTrue monthlyGap per monthGap per year
ReflexMD$297.00$540.27$243.27$2,919.24
Zealthy$151.00$379.00$228.00$2,736.00
Nu Image Medical$99.00$310.16$211.16$2,533.92
BetterMe Rx$99.00$303.29$204.29$2,451.48
AM Rx$106.00$297.00$191.00$2,292.00
Fella Health$149.00$325.03$176.03$2,112.36
Sprout Health$149.00$325.03$176.03$2,112.36
Revive Meds$199.00$369.00$170.00$2,040.00

And the advertised figure is frequently not the billed one, which is what the chart above is measuring. A seller quoting less than the brand on its landing page may still cost more once the billing cycle is restated as a calendar month — see how we verify.

Twelve months of it

  • VitaStir — price climbs with dose
  • Bodi Envi — one price at every dose
  • Wegovy, direct from the manufacturer
$0$1,000$2,000$3,000$4,000$5,000cumulative spendBodi Envi is ahead from month 2VitaStir, month 1: $153.27 spent so farVitaStir, month 2: $436.99 spent so farVitaStir, month 3: $775.06 spent so farVitaStir, month 4: $1,167.48 spent so farVitaStir, month 5: $1,614.26 spent so farVitaStir, month 6: $2,061.04 spent so farVitaStir, month 7: $2,507.82 spent so farVitaStir, month 8: $2,954.60 spent so farVitaStir, month 9: $3,401.38 spent so farVitaStir, month 10: $3,848.16 spent so farVitaStir, month 11: $4,294.94 spent so farVitaStir, month 12: $4,741.72 spent so farBodi Envi, month 1: $155.00 spent so farBodi Envi, month 2: $310.00 spent so farBodi Envi, month 3: $465.00 spent so farBodi Envi, month 4: $620.00 spent so farBodi Envi, month 5: $775.00 spent so farBodi Envi, month 6: $930.00 spent so farBodi Envi, month 7: $1,085.00 spent so farBodi Envi, month 8: $1,240.00 spent so farBodi Envi, month 9: $1,395.00 spent so farBodi Envi, month 10: $1,550.00 spent so farBodi Envi, month 11: $1,705.00 spent so farBodi Envi, month 12: $1,860.00 spent so farWegovy, month 1: $379.38 spent so farWegovy, month 2: $758.76 spent so farWegovy, month 3: $1,138.14 spent so farWegovy, month 4: $1,517.52 spent so farWegovy, month 5: $1,896.90 spent so farWegovy, month 6: $2,276.28 spent so farWegovy, month 7: $2,655.66 spent so farWegovy, month 8: $3,035.04 spent so farWegovy, month 9: $3,414.42 spent so farWegovy, month 10: $3,793.80 spent so farWegovy, month 11: $4,173.18 spent so farWegovy, month 12: $4,552.56 spent so far$4,741.72VitaStirVitaStir$4,552.56WegovyWegovy$1,860.00Bodi EnviBodi Envi136912months on treatment
VitaStir has the lowest first-month cost among these examples: $153.27. By month 2, Bodi Envi has cost less in total. Over 12 modeled months, VitaStir totals $4,741.72. Bodi Envi totals $1,860.00.

Modeled cumulative cost equivalents, not fill invoices or dosing advice. One published price step per calendar month, then held at the top; this does not imply matching doses between products. Both brand and compounded charges are normalized to 30.4375 days. Introductory offers are excluded. Wegovy ongoing injection pricing is assumed to continue. This is not a prediction of future pricing. Known mandatory recurring fees are included, including required recurring shipping or consultation charges. One-time charges and optional extras are excluded. Sellers with an unpriced mandatory recurring fee are not charted. Brand: $349 per 28-day fill = $379.38 per calendar month, injection 0.25–2.4 mg only; introductory offer excluded.

Cumulative spend by month for VitaStir, Bodi Envi, Wegovy.
MonthVitaStir (spent so far)Bodi Envi (spent so far)Wegovy (spent so far)
Month 1$153.27$155.00$379.38
Month 2$436.99$310.00$758.76
Month 3$775.06$465.00$1,138.14
Month 4$1,167.48$620.00$1,517.52
Month 5$1,614.26$775.00$1,896.90
Month 6$2,061.04$930.00$2,276.28
Month 7$2,507.82$1,085.00$2,655.66
Month 8$2,954.60$1,240.00$3,035.04
Month 9$3,401.38$1,395.00$3,414.42
Month 10$3,848.16$1,550.00$3,793.80
Month 11$4,294.94$1,705.00$4,173.18
Month 12$4,741.72$1,860.00$4,552.56

Over a year the gap is what a reader should actually be weighing, because STEP 4 found the weight returning after the drug stopped. A monthly saving is only a saving if the year is affordable.

What you are actually trading3

Below the brand’s price you are buying a preparation with no label of its own, no FDA review of its manufacturing, and a concentration set by the pharmacy rather than by an approved specification. Above it, you are buying all of that and paying more than the approved product costs.

What is actually different →

And if the comparison you are really making is with the other compounded molecule — what the same sellers charge for tirzepatide — that is on compounded semaglutide vs compounded tirzepatide.

Sources

  1. Wegovy manufacturer cost and coverage terms, checked October 13, 2026 Source
  2. This site's price index, computed from what sellers actually bill Read it
  3. FDA prescribing information for WEGOVY (semaglutide), revision 6/2026 DailyMed