Compounded semaglutide

Nucore Health review

Nucore Health's compounded semaglutide injections are listed from $179 a month. No membership fee is charged. The listing says "as low as" and names no dose, so ask for the figure that matches your prescription.

A real month costs$179139 of 379 by price
EvidenceVerified
Billing cyclemonthly
Price across dosesClimbs with the dose
Where it shipsClaims every state
FDA warning letterNone found

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Is it right for you?

Worth a look if

  • You're new to GLP-1s and expect the first month on a starter dose while your body adjusts.
  • You like having a needle-free oral semaglutide on the same menu in case injections don't suit you.
  • You want a plan for tapering, since Nucore starts lowering doses once your BMI reaches 25.

Skip it if

  • You need a firm per-dose price list before you commit.
  • Emailing a cancellation three days ahead of each renewal sounds like one chore too many.

What's included

Three GLP-1 options appear on Nucore's treatment page: semaglutide injections from $179 a month, an oral semaglutide at a slightly higher starting figure, and tirzepatide from $269. None carries a membership fee. Refills can be set to renew every 30 or 90 days.

Nucore says its compounded semaglutide uses the base form of the drug, not a salt form. It also says the ingredients are pharmaceutical grade rather than research grade. The dispensing pharmacy isn't named. Nucore lists OpenLoop Health among the partners behind its providers, pharmacies and operations.

From sign-up to refills

  1. Pick semaglutide, complete Nucore's online medical intake, and pay for the first billing cycle.
  2. A licensed provider reviews it. If a live telehealth visit is required, the medication is ordered after that visit.
  3. Approved orders typically leave the pharmacy within 1 to 2 business days, packed cold.
  4. Expect monthly follow-ups while your dose is still climbing. Once it's steady, visits drop to every three months.
  5. Each visit needs a fresh weight, blood pressure and heart rate reading from you.

What's good, what isn't

What's good

  • Semaglutide starts at $179 a month at Nucore, with no membership fee on top.
  • Base-form semaglutide, not a salt form, is what Nucore says its pharmacy compounds.
  • An oral semaglutide on Nucore's menu gives you a needle-free option at a slightly higher starting price.

What isn't

  • Nucore labels the semaglutide price "as low as" and publishes no dose-by-dose figures.
  • Canceling means emailing Nucore support at least 72 hours before the billing date, or paying for one more cycle.
  • Refunds at Nucore generally end once the pharmacy has ordered, dispensed or shipped your medication.

Read these terms first

Your quoted price
Confirm the monthly charge for your prescribed dose, and whether it renews every 30 or 90 days.
Ordering happens early
For new patients who need no live visit, Nucore orders the medication when the intake is submitted. After that point, refunds are generally off the table.
Cold-pack shipping days
Cold-packed orders ship Monday through Thursday only. An approval late in the week can wait until the following Monday.

Price

Nucore Health costs $179 a month for compounded semaglutide. That is the starting dose, and it rises as your dose does.

How we got $179

The arithmeticOne month = 30.4375 days

  1. Nucore Health advertises

    Read on Nucore Health's own site

    $179.00

  2. The card is charged $179.00 — exactly what it advertises

    + $0.00

  3. And it is charged once a calendar month

    + $0.00

A real month$179.00

Reconciles exactly — the advertised figure is a real month.

The price above is the starting dose, and it rises as your dose does. This seller does not publish how far, so treat it as an entry price rather than what you will be paying in six months.

Where it sits, and what costs less

$54median $199$325+

138 cheaper · 36%224 dearer · 59%

The most expensive 10 sellers charge between $325 and $540 a month.

  1. Fidelity Medical Clinicstarting dose$54
  2. Collective$76
  3. NextMeds$79
  4. Lean Meds$79
  5. RxPepsDirectstarting dose$80
  6. Nucore Health$179

Another 133 sellers are cheaper than Nucore Health. The whole cheapest list →

Where it says it operates

Nucore services are available nationwide in all 50 states.

Read on its own site in August 2026. That is the seller’s own promise for the whole country, so confirm your state when you sign up.

What else this seller sells

The same seller appears in our data for one other medication.

Each figure is a real month for that medication, and none of it is part of the compounded semaglutide price above. How the two molecules compare at every seller that sells both: compounded semaglutide vs compounded tirzepatide.

Common questions about Nucore Health

Is Nucore Health a legitimate telehealth provider?
Nucore Health says it is physician owned, and licensed providers make every prescribing decision. OpenLoop Health is among its partners. Compounded semaglutide isn't Wegovy or Ozempic. Nucore's own disclaimer says compounded drugs aren't reviewed or approved by the FDA for safety, efficacy or quality.
How much does Nucore Health semaglutide cost?
Injections are listed as low as $179 a month and tirzepatide as low as $269. There's no membership fee. The page doesn't give prices by dose.
Can I use FSA or HSA at Nucore Health?
Yes. Nucore lists its GLP-1 treatments as FSA and HSA eligible, and says no insurance is needed.
How do I cancel Nucore Health?
Email Nucore support. Send it more than 72 hours before the next billing date, or that cycle may still be charged. Access continues until the paid period ends.