Compounded semaglutide
Rx.com review
A single month of compounded semaglutide from Rx.com costs $175, and the dose can run from 0.25 mg up to 2.4 mg without that changing. The banner advertising a far lower rate refers to the 12-month plan, paid in one go. Refills never go out on autopilot; you confirm each one.
Is it right for you?
Worth a look if
- You're starting semaglutide for the first time and want a price that won't rise as you titrate.
- You like the idea of approving every refill before your card is touched.
- You want visits, supplies and cold shipping bundled with no separate fees.
Skip it if
- You're in Alaska, where Rx.com's program isn't offered.
- The low 12-month headline is the price you want but you can't pay a year upfront.
What's included
Semaglutide comes in four plan lengths. One month is $175. The 3-, 6- and 12-month plans cost less per month, and each is charged as one total at checkout. Your provider can adjust the dose anywhere from 0.25 mg to 2.4 mg and the plan price stays put.
The provider price index puts Rx.com’s recorded cost on the same calendar-month basis as other sellers. Check whether the quote covers your prescribed dose and includes the same services. Among the sellers we work with, the HealthRX review and the YourEra review cover the sellers nearest in recorded price; we may earn a commission from those sellers.
Included: the online visit, follow-ups and dose changes, syringes and alcohol pads, a dosing guide, cold-packed discreet shipping and unlimited care-team messaging. Rx.com says there are no visit fees, membership fees, dose upcharges or shipping charges.
Behind the site is Rx Platform LLC. MD Integrations supplies the prescribers, and Manifest Pharmacy in Greer, South Carolina, fills the prescriptions.
From sign-up to refills
- Start the quiz with your height, current and goal weight. It estimates your BMI and asks about your goals and habits.
- Enter your state, date of birth and sex, then create an account to see the plans.
- Pick semaglutide and a plan, pay, and finish the health questionnaire with a photo ID. A few states also require a short video visit.
- A provider licensed in your state reviews the visit, usually within 24 hours. Rx.com's shipping policy says approved orders typically ship within 2 to 4 business days.
- When a refill is due, the care team checks in first. You confirm before anything is charged or sent.
What's good, what isn't
What's good
- The monthly price stays at $175 on 0.25 mg and on 2.4 mg alike.
- No automatic renewals: each Rx.com refill waits for your go-ahead before it ships or bills.
- Manifest Pharmacy and MD Integrations are both named in Rx.com's footer.
What isn't
- The headline rate on Rx.com's banner needs a 12-month plan paid in one payment.
- Alaska is excluded; the program covers the other 49 states.
- Medication can't be returned once shipped, per the “Returns & Refund Policy” page.
Read these terms first
- The banner price
- The rate in the banner and on the start page is the 12-month plan. Compare it with the 1-month plan at $175 before you choose.
- If you're not approved
- Rx.com says you aren't charged for medication when a provider decides semaglutide isn't right for you, and its refund policy promises a full refund in that case.
- Who qualifies
- Adults with a BMI of 30 or more, or 27 or more with a condition such as high blood pressure or sleep apnea. The provider makes the final call.
Price
Rx.com costs $175 a month for compounded semaglutide.
How we got $175
The arithmeticOne month = 30.4375 days
Rx.com advertises
Read on Rx.com's own site
$175.00
The card is charged $175.00 — exactly what it advertises
+ $0.00
And it is charged once a calendar month
+ $0.00
A real month$175.00
Reconciles exactly — the advertised figure is a real month.
Where it sits, and what costs less
$54median $199$325+
129 cheaper · 34%238 dearer · 63%
The most expensive 10 sellers charge between $325 and $540 a month.
- Fidelity Medical Clinicstarting dose$54
- RxPepsDirectstarting dose$65
- Collective$76
- NextMeds$79
- Lean Meds$79
- Rx.com$175
Another 124 sellers are cheaper than Rx.com. The whole cheapest list →
Where it says it operates
We currently serve 49 states (all except Alaska). Some states require a short video visit, which is handled during intake.
Read on its own site. It excludes Alaska. That is the seller’s own promise for the whole country, so confirm your state when you sign up.
State pages this seller appears on: AL AZ AR CA CO CT DE DC FL GA HI ID IL IN IA KS KY LA ME MD MA MI MN MS MO MT NE NV NH NJ NM NY NC ND OH OK OR PA RI SC SD TN TX UT VT VA WA WV WI WY
What else this seller sells
The same seller appears in our data for one other medication.
- tirzepatide — $285 a month
Each figure is a calendar-month equivalent. These medications are priced separately from compounded semaglutide. How the two molecules compare at every seller that sells both: compounded semaglutide vs compounded tirzepatide.
Common questions about Rx.com
- Is Rx.com legit?
- Yes, in the sense that real licensed providers and a licensed pharmacy are involved. Rx.com connects you with MD Integrations prescribers, and Manifest Pharmacy dispenses. The semaglutide is compounded, which means it isn't Wegovy or Ozempic and isn't FDA-approved.
- How much does Rx.com semaglutide cost per month?
- $175 for a single month, at every dose. Longer plans bring the monthly rate down, but you pay the full term at checkout. For comparison, a month of Rx.com's compounded tirzepatide is $285.
- Does Rx.com take insurance for semaglutide?
- No. It's self-pay by debit or credit card, and Rx.com says many HSA and FSA cards are accepted.
- How do refills work at Rx.com?
- Your plan doesn't renew by itself. Before each refill the care team checks in, and nothing ships or is charged until you confirm. You can pause or cancel from your account with no fees.